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Alopecia areata foundation

What Is alopecia areata?

pattern baldness is considered an autoimmune disease, in which the immune system, which is designed to protect the body from foreign invaders such as viruses and bacteria, mistakenly attacks the hair follicles, the tiny cup-shaped stopped from which hairs grow, alopecia areata foundation. This can lead to baldness on the scalp and other places.

In most cases, hair falls out in tiny, round patches about the size of a dime. In many situations, the condition does not extend beyond a couple of patches. In some persons, hair loss is more extensive. Although uncommon, alopecia areata foundation, the disease can go on to to cause total loss of hair on the head (referred to as alopecia totalis) or complete loss of hair on the head, face, and body (alopecia universalis).

What Causes It?

In male or female pattern baldness, immune system cells known as white blood cells attack the speedily growing cells in the hair follicles that make the hair. The affected hair follicles become small and radically impede hair production. Fortunately, the stem cells that continually supply the follicle with new cells do not seem to be targeted. Therefore the follicle always has the potential to regrow hair - alopecia areata foundation.

Researchers do not know precisely why the hair follicles undergo these changes, alopecia areata foundation but they are fairly sure that a combination of genes may predispose some citizens to the affliction. In those who are genetically predisposed, some type of trigger - perhaps a virus or a certain element in the person's environment - brings on the assault against the hair follicles.

Who Is Most Likely To Get It?

male or female pattern baldness affects around four million American citizens of both sexes and of all ages and ethnic backgrounds. It often begins in childhood alopecia areata foundation.

If you happen to have a close relation with the ailment, your risk of developing it is slightly increased. If your relative lost her or his first patch of hair before age 30, the risk to other family members is greater. Generally speaking, one in five folks that are afflicted with the ailment have a family member who has it as well.

Is My alopecia areata a Symptom of a Serious Disease?

pattern baldness is not a life-threatening disease and neither is alopecia areata foundation. It does not instigates any physical pain, and people that are affected by the ailment are generally healthy otherwise. For most folk however, a affliction that unpredictably seriously affects their appearance the way alopecia areata does is a serious matter.

The effects of male or female pattern baldness are primarily socially and emotionally worrying. In alopecia universalis, however, loss of eyelashes and eyebrows and hair in the nose and ears can make the person more susceptible to dust, germs, and foreign particles entering the ears, nose, and eyes.

pattern baldness often occurs in individuals whose relations have other autoimmune conditions, such as diabetes, rheumatoid arthritis, systemic lupus erythematosus, pernicious anemia, Addison's disease or thyroid disease or even alopecia areata foundation. People who have male or female pattern baldness do not typically have other autoimmune conditions, but they do have a higher occurrence of asthma, thyroid disease, atopic eczema and nasal allergies, alopecia areata foundation.

Can I Pass It on to My Children?

It is possible, but not likely, for pattern baldness to be inherited. Most children with alopecia areata do not have a father or mother with the affliction, and the vast majority of parents with pattern baldness do not pass it along to their children. male or female pattern baldness is not like some genetic conditions in which a child has a fifty fifty chance of developing the disease if one parent has it. Scientists believe that there may be a number of genes that predispose certain persons to the ailment. It is highly unlikely that a child would inherit all of the genes necessary to predispose him or her to the affliction.

Even with the right (or wrong) combination of genes, alopecia areata is not a certainty. In identical twins, who share all of the same genes, the concordance rate is only 55 percent. In other words, if one twin has the disease, there is only a fifty five percent chance that the other twin will have it too. This shows that other factors besides genetics are needed to trigger the ailment.

To learn more with regard to the genes and other considerations involved in male or female pattern baldness risk, the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is funding an pattern baldness registry alopecia areata foundation. The registry is a well planned network of five centers throughout the United States of America that will identify and register patients with the condition and collect data and blood samples (which contain genes). Data, including genetic information, will be made available to hair research scientists studying the genetic origin and other aspects of disease and disease risk. (For more information with reference to the registry, see "How Can I Take Part In Research?")

Will My Hair Ever Grow Back?

There is an excellent chance that your hair will grow back again, but it could also fall out again. Unfortunately however, it is impossible to predict when it may regrow or fall out. The course of the disease varies from person to person. Some citizens lose just a few patches of hair, alopecia areata foundation after which the hair regrows and the disease never recurs. Other individuals continue to lose and regrow hair for many years. Some people lose all the hair on their head, face and body; others lose all the hair on their head. Even for those unfortumate folk who suffer from total hair loss, the possibility for full regrowth remains.

In some, the initial hair re-growth is white, with a gradual return of the original hair color. In most, the re-grown hair is ultimately the same color and texture as the original hair.

What Can I Expect Next?

The course of alopecia areata is highly unpredictable, and the uncertainty of what will happen next is probably the hardest and most frustrating effect of the condition. You may continue to lose hair, or your alopecia may stop, alopecia areata foundation. Your lost hair could grow back but it may not and it is possible that you may not continue to develop new bare patches.

How Is It Treated?

[While there is neither a cure for pattern baldness nor drugs approved for its treatment], some people find that drugs approved for other purposes like pattern baldness can help hair grow back, alopecia areata foundation at least temporarily. The following are some treatments for male or female pattern baldness. Keep in mind that while these methods of treatment may promote hair growth, none of them prevent new patches or in fact cure the underlying affliction. Consult your health care professional with reference to the best option for you.

  • Corticosteroids - Corticosteroids are powerful anti-inflammatory drugs, alopecia areata foundation, similar to a hormone called cortisol produced in the body. Because these drugs suppress the immune system if given orally, they are often used in the treatment of several autoimmune diseases, including alopecia areata foundation. Corticosteroids may be taken in 3 ways for alopecia areata:

  • Local innoculations - Injections of steroids directly into hairless patches on the scalp and sometimes the brow and beard areas are effective in hair growth in most folks. It habitually takes about 4 weeks for new hair growth to become visible. Injections deliver tiny amounts of cortisone to problem areas, avoiding the more serious side effects encountered with long-term oral use. The main side effects of injections are passing pain, mild swelling, and occasionally changes in pigmentation, as well as small indentations in the skin that go away when injections are stopped. Because innoculations can be painful, they may not be the preferred treatment for children. After 1 or 2 months, new hair growth generally becomes visible, and the injections ordinarily have to be repeated monthly. The cortisone removes the confused immune cells and allows the hair to grow. Large areas cannot be treated, however, because the discomfort and the volume of medicine become too great and can result in side effects similar to those of the oral regimen.

  • Oral corticosteroids - Corticosteroids taken orally are a mainstay of treatment for many autoimmune diseases and may be used in more extensive male or female pattern baldness. But because of the risk of side effects of oral corticosteroids, such as hypertension, alopecia areata foundation and cataracts, they are used only occasionally for pattern baldness and for shorter periods of time.

  • Topical ointments - ointments or creams containing steroids rubbed directly onto the affected area are less traumatic than innoculations and, therefore, are occasionally preferred for children. However, corticosteroid ointments and creams alone are less effective than innoculations; they work best when combined with other topical methods of treatment, such as minoxidil or anthralin.

  • Minoxidil (5%) (Rogaine) - Topical minoxidil tincture promotes hair growth in several conditions in which the hair follicle is tiny and not growing to its full potential. Minoxidil is FDA-approved for treating male and female pattern loss of hair. It may also be useful in promoting hair growth in alopecia areata. The mixture, applied twice daily, has been shown to promote hair growth in both adults and children, and may be used on the scalp, brow, and beard areas. With regular and proper use of the solution, new hair growth happens in about 3 months.

  • Brand names included in this article are provided as examples only, and their inclusion does not mean that these products are endorsed by the National Institutes of Health or any other Government agency. Also, if a particular brand name is not mentioned, this does not mean or imply that the product is unsatisfactory.

  • Anthralin (Psoriatec) - Anthralin, a synthetic tar-like substance that changes immune function in the problem skin, is an approved treatment for psoriasis. Anthralin is also commonly used to treat male or female pattern baldness. Anthralin is applied for 20 to 60 minutes ("short contact therapy") to avoid skin irritation, alopecia areata foundation which is not needed for the drug to work. When it works, new hair growth is commonly evident in two to three months. Anthralin is often used in combination with other treatments, such as corticosteroid injections or minoxidil, for improved results.

  • Sulfasalazine - A sulfa drug, sulfasalazine has been used as a treatment for different autoimmune disorders, including psoriasis. It acts on the immune system and has been used to some effect in patients with extremely bad alopecia areata.

  • Topical sensitizers - Topical sensitizers are medications that, when applied to the scalp, instigate an allergic reaction that leads to itching, scaling, and eventually hair growth. If the medication works, new hair growth is customarily established in 3 to 12 months. Two topical sensitizers are used in pattern baldness: squaric acid dibutyl ester (SADBE) and diphenylcyclopropenone (DPCP). Their safety and consistency of formula are currently under review.

  • Oral cyclosporine - Originally developed to keep people's immune systems from rejecting transplanted organs, oral cyclosporine is sometimes used to suppress the immune system response in psoriasis and other immune-mediated skin conditions. But suppressing the immune system can also instigates problems, including an increased risk of serious infection and possibly skin cancer. Although oral cyclosporine may regrow hair in male or female pattern baldness, it does not turn the ailment off. Most physicians feel the dangers of the drug outweigh its benefits for alopecia areata and alopecia areata foundation.

  • Photochemotherapy - In photochemotherapy, a treatment used most commonly for psoriasis, a person is given a light-sensitive drug called a psoralen either orally or topically given and then exposed to an ultraviolet light source. This combined treatment is known as PUVA. In clinical trials, an estimated fifty five percent of folks achieve cosmetically acceptable hair growth using photochemotherapy. However, the relapse rate is high, and patients must go to a treatment center where the equipment is available at least two to three times per week. Furthermore, the treatment carries the risk of developing skin cancer.

  • Alternative therapies - When drug methods of treatment fail to bring acceptable hair re-growth, some persons turn to other types of therapies - alopecia areata foundation. Alternatives purported to help pattern baldness include zinc and vitamin supplements, Chinese herbs, aroma therapy, evening primrose oil, and acupuncture. Because many alternative therapies are not backed by clinical trials, they may or may not be effective for regrowing hair. In fact, some may actually make hair loss worse. Furthermore, just because these are natural therapies does not mean that they are safe. As with any therapy, it is best to discuss these treatments with your family physician prior to employing them.

As well as treatments to help hair grow, there are steps that can be taken to minimize the physical dangers or disadvantages of lost hair.

  • Sunscreens are important for the scalp, face, and all areas of the body that are exposed.

  • Spectacles (or sunglasses) protect the eyes from excessive sunlight, and from dust particles and debris, when eyebrows or eyelashes are missing.

  • Wigs, caps, or scarves protect the scalp from sun and keep the head warm.

  • Antibiotic ointment applied inside the nostrils can help to protect against organisms invading the nose when nostril hair is missing.

How Will alopecia areata Affect My Life and Lifestyle?

This is a common question, particularly for children, teenagers and young adults who are beginning to form lifelong goals and who may live with the effects of male or female pattern baldness for many years, alopecia areata foundation. It is good to know that male or female pattern baldness is not a painful ailment and does not make citizens feel sick physically. It is not contagious, and individuals who have the pattern baldness affliction are generally in good health otherwise. It does not shorten life expectancy and it should not interfere with the ability to achieve such life goals as going to school, working, marrying, raising a family, playing sports, and exercising.

The emotional effects of living with loss of hair, however, can be a challenge. Many persons cope by learning as much as they can with reference to the condition; speaking with others who are facing the same problems; and, if necessary, looking for counseling to help construct a positive self-image. To take account of quality-of-life issues for alopecia areata foundation, alopecia areata and all other skin diseases, the NIAMS sponsored a scientific meeting in September 2002 on the burden of skin diseases.

How Can I Deal With With the Effects of This Disease?

Living with alopecia can be hard, especially in a culture that sees hair as a sign of youthfulness and good health. Even so, most individuals with alopecia areata are well-adjusted, happy folks living full lives.

The key to coping is valuing yourself for who you are, not for the amount of hair you may or may not have. Many citizens learning to deal with male or female pattern baldness find it helpful to talk with other people who are dealing with the same problems. More than 4 million citizens across the country have this disease at some point in their lives, so always remember that you are not in isolation. If you would like to be in touch with others with the ailment, the National pattern baldness Foundation (NAAF) can help through its pen pal program, message boards, annual conference, and support groups that meet in various situations nationwide.

Another way to cope with the condition is to lessen its effects on your appearance. If you have total baldness, a wig or hairpiece can look natural and stylish. For small patches of loss of hair, a hair colored powder, cream or crayon applied to the scalp can make hair loss less obvious by getting rid of the contrast between the hair and the scalp. Skilfully applied alopecia areata foundation eyebrow pencil can mask missing eyebrows.

Children with alopecia areata may prefer to wear bandanas, scarves or caps. There are many types available to suit a child's interest and mood - a lot even have ponytails fixed on to them with alopecia areata foundation.

For women, attractive scarves can hide patchy baldness; jewelry and clothing can distract attention from patchy hair; and proper makeup can hide the effects of lost hair on the face. If you would like to learn more about covering up the cosmetic effects of alopecia areata foundation pattern baldness, ask your doctor or members of your local support group to recommend a cosmetologist who specializes in working with folks whose appearance is problem by medical conditions.

Is Research Close to Finding Better Treatments or a Cure?

While a cure is not imminent, researchers are making headway toward a better understanding of the affliction. This increased understanding will likely lead the way to better methods of treatment for male or female pattern baldness and eventually a way to prevent or even cure it.

Alopecia research ranges from the most basic studies of the mechanisms of hair growth and alopecia in mice to testing medicines and ways to apply medicines to help regrow hair in persons. Both the National Institutes of Health and the National pattern baldness Foundation support research into the alopecia areata foundation pattern baldness disease and its treatment. Here are some areas of research that hold promise:

  • Developing an animal model - This is a critical initial step toward understanding the affliction, and much progress has been made. By developing a mouse with a condition similar to human male or female pattern baldness, researchers into hair disease hope to learn more with reference to the mechanism of the ailment and in the end develop immune system methods of treatment for the disease in people.

  • Mapping genes - Researchers into hair disease are investigating the possible genetic causes and mechanism of the affliction both in families that have one or more persons with the ]disease] and in the general population. An understanding of the genetics of the condition will aid in disease prevention, early intervention, and development of specific therapies.

  • Studying hair follicle development - By investigating how hair follicles form in mouse embryos, scientists hope to gain a better understanding of hair cycle biology that may lead to treatments for the underlying ailment process.

  • Targeting the immune system - Several new agents found to be effective in treating psoriasis may prove to be effective in alopecia areata foundation alopecia areata. These medicines work by blocking certain chemical messengers that play a role in the immune response, or by interfering with the activity of white blood cells (called T-cells) that are involved in the immune system's assault on hair follicles. Recently developed therapies for treating other autoimmune diseases like rheumatoid arthritis and lupus may also benefit patients with alopecia areata foundation male or female pattern baldness.

  • Finding better ways to administer drugs - One limitation of current topical therapies is getting the drug to the source of the difficulties, alopecia areata foundation. Hair research scientists are looking for a substance that penetrates the fat layer under the skin to deliver medication directly to hair follicles. In laboratory animals, topically applied synthetic sacs known as liposomes seem to fit the bill. Studies are still appropriate to show whether liposomes achieve the same results for individuals.

  • Understanding cytokines - Chemical messengers known as cytokines (alopecia areata foundation) play a role in regulating the body's immune response, whether it is the standard response to a foreign invader such a virus or an abnormal response to a part of the body. Scientists believe that by giving certain cytokines that inhibit inflammation, it may be possible to impede or stop the body's unusual response to the hair follicles. Because giving the cytokines (alopecia areata foundation) systemically may cause unwanted effects, they believe a topical medication using liposomes to get the media to the root of the hair inside the follicle may be preferable.

  • Understanding stem cell biology - Epithelial stem cells are immature cells that are responsible for regenerating and maintaining a variety of tissues, including the skin and the hair follicles. Stem cells in the follicle appear to be spared from injury in alopecia areata, which may explain why the potential for regrowth is always there in persons that have the affliction. By studying the biology of these cells, and their immediate offspring, which seem to be targeted by the immune system, Hair research scientists hope to gain a better understanding of considerations that trigger the condition.

As a footnote, pattern baldness has millions of suffers all over the world - you are not alone if you have the affliction too. Remember that many folks adversely affect their lives in a negative way by focussing on the ailment when perhaps they should be concentrating on their lives instead. Almost all of the people that you come across will judge you by your attitude, your general demeanor and your personality - not by the amount of hair you have on your head. This has been a long alopecia areata foundation article and we hope that it has been of use to you. We would like to thank the website Hair Loss Problems for kindly allowing us to reproduce it.

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DISCLAIMER: the information  published on this site are for general use only. They should not be considered as medical advice and like any physical ailments a health care professional should be consulted.